Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Assessment, 2023 | In-depth Insights into the Clinical Trials, Emerging Drugs, Latest FDA, EMA, and PMDA Approvals, Treatment Outlook, and Key Companies

February 21 08:50 2023
Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Assessment, 2023 | In-depth Insights into the Clinical Trials, Emerging Drugs, Latest FDA, EMA, and PMDA Approvals, Treatment Outlook, and Key Companies
Delveinsight Business Research LLP
As per DelveInsight’s assessment, globally, about 12+ key pharma and biotech companies are working on 12+ pipeline drugs in the Alpha-1 Antitrypsin Deficiency (AATD) therapeutics landscape based on different Routes of Administration (ROA), Mechanism of Action (MOA), and molecule types. Several of the therapies are in the advanced stages of clinical development and are expected to launch in the coming years.

Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Insight, 2023” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Alpha-1 Antitrypsin Deficiency Market. 

The Alpha-1 Antitrypsin Deficiency Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase.  The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.

Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Analysis

Alpha-1 Antitrypsin Deficiency (AATD) Pipeline Analysis

The report provides insights into: 

  • The report provides detailed insights into the emerging therapies for the treatment of Alpha-1 Antitrypsin Deficiency and the aggregate therapies developed by major pharma companies.

  • It accesses the different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of clinical development.

  • It outlines the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

  • The report evaluates the drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 

  • It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Alpha-1 Antitrypsin Deficiency market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.  

Analysis of Emerging Therapies by Phases

The report covers the emerging products under different phases of clinical development like –

  • Late stage products (Phase III)

  • Mid-stage products (Phase II)

  • Early-stage product (Phase I) 

  • Pre-clinical and Discovery stage candidates

  • Discontinued & Inactive candidates


Route of Administration

Alpha1-Antitrypsin Deficiency (AATD) pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as

  • Oral

  • Parenteral

  • Intravitreal

  • Subretinal

  • Topical


Molecule Types

Products have been categorized under various Molecule types, such as

  • Monoclonal Antibody

  • Peptides

  • Polymer

  • Small molecule

  • Gene therapy


Mechanism of Action of the Emerging Pipeline Therapies

  • Immunomodulators; Serine endopeptidase inhibitors

  • Alpha 1 antitrypsin modulators

  • Alpha 1 antitrypsin inhibitors; RNA interference

  • Leucocyte elastase inhibitors

  • Alpha 1 antitrypsin modulators; RNA interference


Learn How the Ongoing Clinical & Commercial Activities will Affect the Alpha-1 Antitrypsin Deficiency Therapeutic Segment @

Alpha-1 Antitrypsin Deficiency Therapeutics Landscape

There are approx. 12+ key companies developing therapies for Alpha1-Antitrypsin Deficiency (AATD). Currently, Arrowhead Pharmaceuticals is leading the therapeutics market with its Alpha1-Antitrypsin Deficiency (AATD) drug candidates in the most advanced stage of clinical development.

The Leading Companies in the Alpha-1 Antitrypsin Deficiency Therapeutics Market Include:

  • Alnylam Pharmaceuticals

  • Arrowhead Pharmaceuticals

  • Beam Therapeutics

  • Centessa Pharmaceuticals

  • CSL Behring

  • Grifols

  • Inhibrx

  • Kamada

  • Kamada Ltd

  • LFB Biotechnologies

  • Mereo Biopharma

  • Promethera Biosciences

  • Santhera Pharmaceuticals

  • Shire

  • WaVe Life Sciences

And Many Others

Alpha1-Antitrypsin Deficiency (AATD) Drugs Covered in the Report Include

  • ALN-AAT02: Alnylam Pharmaceuticals

  • Alvelestat: Mereo Biopharma)

  • ARO AAT: Arrowhead Pharmaceuticals

  • DCR-A1AT: Dicerna Pharmaceuticals, Inc.

  • INBRX-101: Inhibrx, Inc.

  • Kamada-AAT for Inhalation: Kamada, Ltd.

  • VX-864: Vertex Pharmaceuticals Incorporated

And Many More

Request the Sample PDF to Get a Better Understanding of the Emerging Drugs and Key Companies @


Table of Content (TOC)

1. Report Introduction

2. Executive Summary

3. Alpha-1 Antitrypsin Deficiency Current Treatment Patterns

4. Alpha-1 Antitrypsin Deficiency – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Alpha-1 Antitrypsin Deficiency Late Stage Products (Phase-III)

7. Alpha-1 Antitrypsin Deficiency Mid-Stage Products (Phase-II)

8. Alpha-1 Antitrypsin Deficiency Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Alpha-1 Antitrypsin Deficiency Discontinued Products

13. Alpha-1 Antitrypsin Deficiency Product Profiles

14. Key Companies in the Alpha-1 Antitrypsin Deficiency Market

15. Key Products in the Alpha-1 Antitrypsin Deficiency Therapeutics Segment

16. Dormant and Discontinued Products

17. Alpha-1 Antitrypsin Deficiency Unmet Needs

18. Alpha-1 Antitrypsin Deficiency Future Perspectives

19. Alpha-1 Antitrypsin Deficiency Analyst Review  

20. Appendix

21. Report Methodology

*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

Download Sample PDF to Explore the Key Offerings of the Report @


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About DelveInsight
DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.

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