DelveInsight’s “Pompe Disease Market Insights, Epidemiology, and Market Forecast-2032” report delivers an in-depth understanding of the Pompe Disease, historical and forecasted epidemiology as well as the Pompe Disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom) and Japan
The Pompe Disease market report provides current treatment practices, emerging drugs, market share of individual therapies, market drivers, market barriers, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
Pompe Disease Market
Key Companies working in the Pompe market include Genzyme, Sanofi, Amicus Therapeutics, and many others
Key Therapies included in the Pompe market includes Alglucosidase Alpha, Actus -101, AT845 and many others
Pompe Disease Overview
Pompe disease, a severe metabolic myopathy, is caused by mutations in the gene coding for acid alpha-glucosidase (GAA), the enzyme that breaks down glycogen in the acidic milieu of the lysosome. Once in the lysosome, glycogen can escape following complete degradation by GAA in the form of glucose. A deficiency of the enzyme leads to lysosomal accumulation of glycogen in multiple tissues, but cardiac and skeletal muscles are most severely affected. The disease also goes by the name “Type II glycogen storage disease (GSDII)” or “Acid maltase deficiency.” It is named after a Dutch pathologist, Johannes Cassianus Pompe, who described an autopsy of a 7-month-old girl diagnosed with “idiopathic myocardial hypertrophy” and generalized muscle weakness.
Pompe Disease Epidemiology
Pompe Disease in Europe
Finland has a population of approximately 5 million and has the lowest incidence of GAA deficiency, with only 2 reported cases of infantile Pompe disease and 1 case of adult-onset.3 The incidence in the Netherlands was estimated to be 1 in 40,000. Newborns were screened using newborn Guthrie cards and analyzed for the 3 most common mutations (IVS1(-13T→G), 525delT, and delexon18) seen in GAA deficiency in the Dutch population. Other mutations that account for milder disease and presentation in adulthood were not considered, so the true incidence is likely higher.
Pompe Disease in North America
In the United States, one study found the incidence of GAA deficiency disease to be higher than previously published estimates. The prevalence rate observed was 1 in 21,979.
In Mexico, a study was conducted and detected an incidence rate of 1 in 27,800.
The Report Covers the Pompe Disease Epidemiology Segmented by –
Pompe Disease prevalent cases
Pompe Disease incident cases
Pompe Disease diagnosed cases
Pompe Disease treatment cases
Click here to learn more about the Pompe Disease Market Landscape
Pompe Disease Market Outlook
The Pompe Disease market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Pompe Disease market trends by analyzing the impact of current Pompe Disease therapies on the market, unmet needs, drivers and barriers, and demand for better technology.
This segment gives a thorough detail of the Pompe Disease market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. According to DelveInsight, the Pompe Disease market in 7MM is expected to witness a major change in the study period 2019-2032.
Key Companies Working in the Pompe Disease Market include
And many others
Pompe Disease Therapies Covered in the Report:
Learn more about Key Companies and Emerging Therapies in the Pompe Disease Market
Table of Contents
Executive Summary of Pompe Disease Market
Pompe Disease Background and Overview
Pompe Disease Epidemiology and patient population
Pompe Disease Market Emerging Therapies
Pompe Disease Market Cancer Market Outlook
Market Access and Reimbursement of Therapies
Market Report Methodology
Learn more about detailed report offerings @ Pompe Disease Market Outlook
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